Vaccine Development for Nipah Virus Infection in Pigs

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Nipah virus infection of pigs in peninsular Malaysia.

Between late 1998 and 1999, the spread of a new disease of pigs, characterized by a pronounced respiratory and neurological syndrome, sometimes accompanied by the sudden death of sows and boars, was recorded in pig farms in peninsular Malaysia. The disease appeared to have a close association with an epidemic of viral encephalitis among workers on pig farms. A previously unrecognised paramyxovi...

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Nipah Virus Infection

Nipah virus infection is an emerging disease endemic in Southeast Asia. This virus is carried subclinically in fruit bats of the genus Pteropus, a host to which it seems well adapted. Illnesses caused by Nipah virus were first described in 19981999, during widespread outbreaks among pigs and people in Malaysia. The virus had apparently been transmitted from bats to pigs around 1996, and was the...

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Nipah Virus Infection

Nipah virus infection is an emerging disease endemic in Southeast Asia. This virus is carried subclinically in fruit bats of the genus Pteropus, a host to which it seems well adapted. Illnesses caused by Nipah virus were first described in 19981999, during widespread outbreaks among pigs and people in Malaysia. The virus had apparently been transmitted from bats to pigs around 1996, and was the...

متن کامل

Nipah Virus Infection

Nipah virus infection is an emerging disease endemic in Southeast Asia. This virus is carried in fruit bats of the genus Pteropus, a host to which it seems well adapted. It emerges periodically to affect humans, pigs and occasionally other domesticated animals. Nipah virus infections were first described during widespread outbreaks that occurred in Malaysia in 1998-1999. The virus had apparentl...

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Recombinant Measles Virus Vaccine Expressing the Nipah Virus Glycoprotein Protects against Lethal Nipah Virus Challenge

Nipah virus (NiV) is a member of the genus Henipavirus, which emerged in Malaysia in 1998. In pigs, infection resulted in a predominantly non-lethal respiratory disease; however, infection in humans resulted in over 100 deaths. Nipah virus has continued to re-emerge in Bangladesh and India, and person-to-person transmission appeared in the outbreak. Although a number of NiV vaccine studies have...

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ژورنال

عنوان ژورنال: Frontiers in Veterinary Science

سال: 2019

ISSN: 2297-1769

DOI: 10.3389/fvets.2019.00016